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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4620c69ecdc0b464f742c508ff9247d77ee63b53c3a5bf930f368c6a28c150a7' 
  AND token = 'mq11Nyu4E/uWMjlChkHBp0FbgHp7fLaUSh0Esdty/Vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}